INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
发明人:
EKSER, BURCIN
申请号：
CA3089840
公开号：
CA3089840A1
申请日:
2019.01.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Provided herein are genetically modified pigs, porcine organs, tissue, and cells having a reduced propensity to cause a rejection response in a human subject following xenotransplantation. In particular, provided herein are genetically modified pigs lacking nonGal xenoantigens, and porcine cells, tissues, and organs obtained from such genetically modified pigs that are suitable for transplantation into a human. Also provided herein are methods of improving a rejection related symptom in a human subject.
