ECKELMAN, BRENDAN,TIMMER, JOHN,RAZAI, AMIR,DEVERAUX, QUINN,JONES, KYLE,NGUY, PETER L.
申请号:
PL13746964
公开号:
PL2812443T3
申请日:
2013.02.06
申请国别(地区):
PL
年份:
2020
代理人:
摘要:
This invention provides an isolated monoclonal antibody that binds to CD47 or an immunologically active fragment thereof, wherein the antibody does not cause a significant level of agglutination of cells after administration. The invention further provides the antibody or an immunologically active fragment thereof for use in a method of alleviating a symptom of a cancer or other neoplastic condition. The invention also provides a pharmaceutical composition comprising the antibody or immunologically active fragment thereof and a carrier.