Eckelman, Brendan,Timmer, John,Razai, Amir,Deveraux, Quinn,Jones, Kyle,Nguy, Peter L.
申请号:
HRP20191500
公开号:
HRP20191500T1
申请日:
2019.08.20
申请国别(地区):
HR
年份:
2019
代理人:
摘要:
This invention provides an isolated monoclonal antibody that binds to CD47 or an immunologically active fragment thereof, wherein the antibody does not cause a significant level of agglutination of cells after administration. The invention further provides the antibody or an immunologically active fragment thereof for use in a method of alleviating a symptom of a cancer or other neoplastic condition. The invention also provides a pharmaceutical composition comprising the antibody or immunologically active fragment thereof and a carrier.