Koncarevic, Alan,Lachey, Jennifer,Seehra, Jasbir,Sherman, Matthew L.
申请号：
AU2010315245
公开号：
AU2010315245A1
申请日:
2010.11.03
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
In certain aspects, the present invention provides compositions and methods for treating fatty liver disease by administering an antagonist of an ActRIIB signaling pathway. Examples of such antagonists include ActRIIB polypeptides, anti-ActRIIB antibodies, anti-myostatin antibodies, anti-GDF3 antibodies and anti-activin A or B antibodies. A variety of hepatic and metabolic disorders may be improved by treating fatty liver disease.
