German Spangenberg,Kathryn Michaela Guthridge,John White Forster,Timothy Ivor Sawbridge,Emma Jane Isobel Ludlow,Jatinder Kaur,Simone Jane Rochfort,Maia Andrea Rabinovich,Piyumi Ekanayake
申请号:
US14692094
公开号:
US20160046901A1
申请日:
2015.04.21
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a method for identifying and/or characterising an endophyte strain, said method including providing a plurality of samples of endophytes, subjecting said endophytes to genetic analysis, subjecting said endophytes to metabolic analysis and selecting endophytes having a desired genetic and metabolic profile.The present invention also relates to novel endophytes having a desired toxin profile wherein the endophyte produces significantly less toxic alkaloids compared with a control endophyte such as standard toxic (ST) endophyte and/or significantly more alkaloids conferring beneficial properties compared with a control endophyte such as ST endophyte.The present invention also relates to endophyte variants having a desired genetic and metabolic profile, wherein said endophyte variants possess genetic and/or metabolic characteristics that result in a beneficial phenotype in a plant harbouring or otherwise associated with the endophyte variant. Preferably said endophyte variants are generated by polyploidisation or induced chromosome doubling.