The present Invention relates to a composition comprising at least one Biological control Agent selected from the group consisting aq746 Bacillus ctiitinosporus (of access 21618 NRRL B -), baciiius mycoides aq726 (of access b21664 NRRL), Bacillus pumilus (of NRRL Access (b) aq717 30087 - baciiius pumilus (of access 21662 NRRL B -), baciilus sp. aq175 (n.Access 55608% TCCA), bacilius (of access aq177 sp. ATCC 35653), Bacillus sp. aq178 (ATCC no. Access 53522), aq743 (of access baciiius subtilis NRRL B - 21665), Bacillus subtilis (of access aq713 NRRL B - 21661), Bacillus subtiis aq153 (of access bacilius Thurin, 55614) ATCC Giensis BD # 32 (of access NRRL B - 21, bacilius thuringiensis aq52 (530).- Access NRRL B - 21619 muscodor albus), 620 (of access NRRL 30547 muscodor roseus), A3 - 5 (of access 30548 NRRL), Rhodococcus globerulus (of access aq719 NRRL B - 21663), Streptomyces galbus (of access 30232 NRRL), Streptomyces sp. NRRL (of access B - 30145), Bacillus thuring Iensis subspec. Kurstaki BMP 123, badilus subtilis aq30002 (n.- Access NRRL B - 50421 30004 (AQ) and Bacillus subtilis.1. Access NRRL B -) and / or a Mutant of these strains have all the identifying characteristics of the respective Strain, and / or a metabolite produced by the strain corresponding to show activity against insects, mites,Plant pathogens and nematodes and / or Fungicide (1) at least one selected from the group consisting of respiratory chain inhibitors in Complex 1 or II in a synergistically effective amount. In addition, the present Invention relates to the use of this composition, as well as a procedure for reducing the overall Damage in plants and parts of plants.La presente invención se refiere a una composición que comprende al menos un agente de control biológico seleccionado del grupo que consiste en Bacillus ctiitinosporus AQ746 (n.° de acceso NRRL B-21618), BaciIIus mycoides AQ726 (n.° de acceso NRRL B21664), Bacillus pumilus (n.° de acceso NRRL B-30087), BaciIIus pumilus A