WANG YUFENG,HU ZILUN,LADZIATA VLADIMIR,GLUNZ PETER W.
申请号：
CL2017000089
公开号：
CL2017000089A1
申请日:
2017.01.13
申请国别(地区):
CL
年份:
2017
代理人:
摘要：
<； p >； This Invention Bertalanffy refers to compounds of the formula (F & amp； (i)； <； / p >；<； p >； * include Summary Sheet structure of figure 13 - 01 - 2017 (pag3) <； / p >；<； p >； or estereois & amp； Taut & acute； groupers, groupers or Pharmaceutical salts thereof & eacute； uticamente acceptable, where all variables are as defined herein. These compounds are Selective inhibitors of Rock.The present Invention also N & amp； n & eacute； refers to pharmaceutical compositions & eacute； Treatment comprising these compounds and to M & eacute； All for treating cardiovascular disorders, disorders of the M Brand； Smooth Muscle Disorders Oncol, & acute； Physiological disorders, neuropatol & amp； GIC Os, autoimmune disorders,Fibr Disorders & acute； ticos and / or inflammatory disorders through its use. <； / p >；LA SOLICITUD SE REFIERE A COMPUESTOS DERIVADOS DE ESPIROCICLOHEPTANO SUSTITUIDO CON UN GRUPO DIHIDROFTALAZINO Ó DIHIDROPIRROLOTRIAZINO, INHIBIDORES DE ROCK , A UNA COMPOSICIÓN FARMACÉUTICA QUE LOS COMPRENDE Y A SU USO EN EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES, INFLAMATORIAS, NEUROPÁTICAS, ENTRE OTRAS.
