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DERIVE DE PYRIDINE MONOCYCLIQUE
专利权人:
EISAI R&D MANAGEMENT CO.; LTD.
发明人:
FUNASAKA, SETSUO,OKADA, TOSHIMI,TANAKA, KEIGO,NAGAO, SATOSHI,OHASHI, ISAO,YAMANE, YOSHINOBU,NAKATANI, YUSUKE,KAROJI, YUKI
申请号:
CA2901585
公开号:
CA2901585C
申请日:
2014.02.18
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention discloses a compound represented by the followingformula (IA) or apharmaceutically acceptable salt thereof(see formula IA)wherein n represents 0 to 2; A represents an arylene group or a heteroarylenegroup; Grepresents a single bond, an oxygen atom or -CH2-; E represents a nitrogen-containingnon-aromatic heterocycle; R1 represents an alkoxy group, an alkoxy alkoxygroup or the like;R2 represents a hydrogen atom, a halogen atom, a hydroxyl group, an alkylgroup, a hydroxyalkyl group, a nitrogen-containing non-aromatic heterocyclic group or thelike; R3 representsa hydrogen atom, an alkyl group, an alkoxy group or the like; and R4represents a C1-6 alkylgroup, with the proviso that when E represents an azetidine ring and R2 or R3is present on anitrogen atom on the azetidine ring, the R2 or R3 does not represent ahydrogen atom.
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