Danielle Elizabeth DETTLING,Yik Andy YEUNG,Kristian Todd POULSEN,Veena KRISHNAMOORTHY,Cesar Adolfo SOMMER
申请号：
US15993874
公开号：
US20180346601A1
申请日:
2018.05.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides antibodies that specifically bind to FLT3 (Fms-Like Tyrosine Kinase 3). The invention further provides bispecific antibodies that bind to FLT3 and another antigen (e.g., CD3). The invention further relates to antibody encoding nucleic acids, and methods of obtaining such antibodies (monospecific and bispecific). The invention further relates to therapeutic methods for use of these antibodies for the treatment of FLT3-mediated pathologies, including cancer such as Acute Myeloid Leukemia (AML).
