COMPOSITIONS DE GARCINOL DESTINEES A LA GESTION THERAPEUTIQUE DU STRESS DU RETICULUM ENDOPLASMIQUE

• 收藏
• 分享

专利权人:

SAMI LABS LIMITED

发明人:

MAJEED, MUHAMMED,NAGABHUSHANAM, KALYANAM,MUNDKUR, LAKSHMI

申请号：

CA3065332

公开号：

CA3065332A1

申请日:

2018.06.22

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Disclosed is the use of garcinol for the therapeutic management of ER stress. More specifically, the invention discloses the ability of garcinol in decreasing ER stress and mitigating toxicity by reducing protein aggregation and decreasing expression of ER stress markers SXBP, GRP78 and ATF4, which indicates translational attenuation and recovery in hyperglycemia, paracetamol, alcohol, thapsigargin and high fat diet induced toxicity models.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/