University of Pittsburgh - of the Commonwealth System of Higher Education
发明人:
Doemling, Alexander
申请号:
AU2011299551
公开号:
AU2011299551A1
申请日:
2011.09.08
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Novel p53-Mdm2 antagonists that conform to Formula I or to Formula II: where the prescribed substituent groups are defined, are useful in treating or preventing cancer. In particular, the compounds and their pharmaceutical compositions are useful for treating relapsed/refractory acute myeloid and lymphoid leukemia and refractory chronic lymphocytic leukemia/small cell lymphocytic lymphomas.