KIM, JUNG KUK,김정국,PARK, YOUNG JIN,박영진,CHOI, IN YOUNG,최인영,JUNG, SUNG YOUB,정성엽,KIM, JUNG KUKKR,PARK, YOUNG JINKR,CHOI, IN YOUNGKR,JUNG, SUNG YOUBKR
申请号：
KR1020170082862
公开号：
KR1020180002544A
申请日:
2017.06.29
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a glucagon derivative, a conjugate thereof, a composition comprising the same, and a use thereof, especially a therapeutic use thereof for metabolic syndrome, hypoglycemia, and congenital hyperinsulinemia. The composition comprising the glucagon derivative of the present invention is a composition comprising peptide with an amino acid sequence represented by general formula 1, X1-X2-QGTF-X7-SD-X10-S-X12-X13-X14-X15-X16-X17-X18-X19-X20-X21-F-X23-X24-W-L-X27-X28-X29-X30, for preventing or treating hyperinsulinemia.본 발명은 글루카곤 유도체, 이의 결합체, 및 이를 포함하는 조성물, 및 이의 용도, 특히 대사증후군, 저혈당증 및 선천성 고인슐린증에 대한 치료적 용도에 관한 것이다.
