The pyrrolin and pyridine inhibitors of ROR- γ农业专利-农业学术服务平台

专利权人:: 生命醫藥有限責任公司;VITAE PHARMACEUTICALS, INC.;生命醫藥公司;生命医药有限责任公司;生命医药公司;Vitae Pharmaceuticals, LLC

发明人:: CLAREMON, David, A.,大卫．A．克莱蒙,大衛．A．克萊蒙,DILLARD, Lawrence, Wayne,劳伦斯．韦恩．迪拉德,勞倫斯．韋恩．迪拉德,DONG, Chengguo,董成国,董成國,FAN, Yi,范怡,JIA, Lanqi,贾兰齐,賈蘭齊,LIU, Zhijie,刘志杰,劉志杰,LOTESTA, Stephen, D.,斯蒂芬．D．罗特斯塔,斯蒂芬．D．羅

摘要：: The present invention provides novel formula (I) compound, pharmaceutically acceptable salt and its pharmaceutical composition, and described pharmaceutical composition is suitable for treatment by the ROR γ disease mediated and illness. Pharmaceutical composition comprising described novel formula (I) compound is also provided and it treats the method in one or more inflammation, metabolism, autoimmunity and Other diseases or illness with what.本發明提供新穎式(I)化合物，其藥學上可接受的鹽，和其藥物組合物，所述藥物組合物適用於治療通過RORγ介導的疾病和病症。還提供包含所述新穎式(I)化合物的藥物組合物和其用於治療一或多種發炎、代謝、自身免疫和其它疾病或病症中的方法。