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IDENTIFICATION OF A JAK2 MUTATION IN POLYCYTHEMIA VERA
专利权人:
发明人:
VAINCHENKER WILLIAM FRANCE,UGO VALERIE FRANCE,JAMES CHLOE FRANCE,LE COUEDIC JEAN PIERRE FRANCE,CASADEVALL NICOLE FRANCE
申请号:
IN3879/DELNP/2007
公开号:
IN301163B
申请日:
2005.10.26
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group, and to the identification of specific inhibitors and siRNA. US2006288432A1
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