Valérie Ugo;William Vainchenker;Jean-Pierre Le Couedic;Nicole Casadevall;Chloé James
发明人:
William Vainchenker,Valérie Ugo,Chloé James,Jean-Pierre Le Couedic,Nicole Casadevall
申请号：
US13213841
公开号：
US20120066776A1
申请日:
2011.08.19
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
