A tissue anomaly detection system (1000), comprising: a probe antenna device (100) structured to radiate an incident radio-frequency signal and irradiate a tissue in near-field conditions so as to produce a resulting radio-frequency signal a receiving device (200) structured to receive the resulting signal and provide corresponding received data and a processing module (300) structured to process the received data to provide an information indicating detection of an anomaly in said tissue. The probe antenna device has a fixed radiation frequency range and is structured so as that the resulting signal is a scattered signal resulting from a combination of the incident signal and an induced radio-frequency signal produced by the radiated tissue.
