A very-simply-structured and easy-to-use device for maintaining negative pressure under the skin which is capable of generating such negative pressure that speeds up the metabolism of the cells under the skin to allow activation of the cells. The device (1) for maintaining negative pressure under the skin comprises a stuck part (10) to be stuck to the skin (S), and a holding part (20) which is placed ON the skin (S) so as to from above cover the stuck part (10) stuck to the skin (S), thereby holding the stuck part (10) at a predetermined position. The stuck part (10) stuck to the skin (S) is lifted and held at the predetermined position by the holding part (20) to maintain the state of the negative pressure generated under the lifted skin (S).
