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Coating composition having excellent oral disintegrating
专利权人:
持田製薬株式会社
发明人:
西村 雅裕
申请号:
JP2013512441
公开号:
JP5690925B2
申请日:
2012.04.26
申请国别(地区):
JP
年份:
2015
代理人:
摘要:
Provided is an outermost layer coating composition for forming a film having a thickness not exceeding 100 µm as the outermost layer on an orally disintegrating tablet, said composition being characterized by including trehalose and/or erythritol, and also including at least one type of water-insoluble inorganic compound selected from the group consisting of water-insoluble inorganic salts, silicic acid compounds, aluminum hydroxide, magnesium oxide, and zinc oxide, each having an average particle size of 0.1 to 50 µm, and/or a water-insoluble fatty acid or a salt or ester thereof. This outermost layer coating composition allows for coated tablets that retain the contradictory characteristics required of orally disintegrating tablets, namely hardness and rapid disintegration, while also ensuring a hard-to-crack smooth surface even if the coating film is thin.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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