It refers to the cycloacrylonitrile derivative in formula (I),where: ring A is C6-C10 aryl or 5-10 membered heteroaryl comprising up to 4 heteroatoms selected from N, O and S； ring B is 4-10 membered heterocycloalkyl comprising up to 3 heteroatoms selected from N, O and S； ring C is monocyclic C3-C7 cycloalkyl, 4- to 7-membered monocyclic heterocycloalkyl comprising up to 4 heteroatoms selected from N, O and S, among others； R1 is halo, C1-C6 alkyl, C2-C6 alkenyl, among others； R2 is halo, C1-C6 alkyl, CN, among others； R3 is halo, C1-C6 alkyl, C2-C6 alkenyl, among others； R4 is halo, C1-C6 alkyl, C2-C6 alkynyl, among others； RZ is H, halo, C1-C6 alkyl, among others； R5 and R6 are H, halo, CN,Among other things, m and Q are 0, 1 or 2； N and P are 0, 1, 2 or 3. The most popular compounds are: (1 - {4 - [(trans-2-phenylacrylonitrile) amino] piperidin-1-il} cyclobutyl； (1-metal-3 - {4 - [(trans-2-phenylacrylonitrile) amino] piperidin-1-il} zetidin-3-il) acetone； among others. He also mentioned a pharmacology composer and a therapeutic approach. These compounds are LSD1 inhibitors and are useful in cancer treatment.Se refiere a derivados de ciclopropilamina de formula (I), donde: el anillo A es arilo C6-C10 o heteroarilo de 5 a 10 miembros que comprende hasta 4 heteroatomos seleccionados de N, O y S； el anillo B es heterocicloalquilo de 4-10 miembros que comprende hasta 3 heteroatomos seleccionados de N, O y S； el anillo C es cicloalquilo C3-C7 monociclico, heterocicloalquilo de 4 a 7 miembros monociclicos que comprende hasta 4 heteroatomos seleccionados de N, O y S, entre otros； R1 es halo, alquilo C1-C6, alquenilo C2-C6, entre otros； R2 es halo, alquilo C1-C6, CN, entre otros； R3 es halo, alquilo C1-C6, alquenilo C2-C6, entre otros； R4 es halo, alquilo C1-C6, alquinilo C2-C6, entre otros； RZ es H, halo, alquilo C1-C6, entre otros； R5 y R6 son H, halo, CN, entre otros； m y q son 0, 1 o 2； n y p son 0, 1, 2 o 3. Son compuestos preferidos: (1- {4-[(trans-2-fenilcicloprop
