Carol Anne Colton,Michael Peter Vitek,Judianne Davis,William E. VanNostrand
申请号：
US12228611
公开号：
US08993833B2
申请日:
2008.08.14
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A modified non-human warm-blooded vertebrate animal in which a biologically active human APP polypeptide is expressed, and in which function of its inducible Nitric Oxide Synthase (iNOS) protein is reduced as compared to a non-modified animal, methods of making the animal, and methods of testing a candidate composition for activity in the treatment of Alzheimers Disease using the animal.
