To provide a composition for inhibiting the formation of hypertrophic scars.SOLUTION: The present invention provides a composition for inhibiting the formation of hypertrophic scars, containing at least one selected from a polypeptide consisting of an amino acid sequence having a dipeptide sequence represented by Pro-Hyp or Hyp-Gly, a chemically modified body thereof or a pharmaceutically acceptable salt thereof.SELECTED DRAWING: None【課題】肥厚性瘢痕の形成を抑制するための組成物を提供すること。【解決手段】Pro-Hyp又はHyp-Glyで示されるジペプチド配列を有するアミノ酸配列からなるポリペプチド、その化学修飾体又はその薬学上許容される塩を少なくとも1種含む、肥厚性瘢痕の形成抑制用組成物。【選択図】なし