Odpornościowe komórki efektorowe wyrażające inżynierowane chimeryczne receptory antygenu swoiste dla CS1

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专利权人:

Ohio State Innovation Foundation

发明人:

YU, JIANHUA,HOFMEISTER, CRAIG,CHU, JIANHONG

申请号：

PL14791494

公开号：

PL2992020T3

申请日:

2014.05.02

申请国别(地区):

PL

年份:

2020

代理人:

摘要：

Disclosed herein are chimeric antigen receptors (CAR) that can specifically recognize tumor- associated antigens (TAA) on multiple myeloma (MM) cells. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with MM that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/