RUNEBERG-ROOS PIA,BESPALOV MAXIM,PENN RICHARD,SAARMA MART
申请号:
NZ59954310
公开号:
NZ599543A
申请日:
2010.10.28
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Patent No. 599543 Disclosed is a neurturin polypeptide,wherein the neurturin polypeptide differs from mature wild-type neurturin by substitution of R63A, or substitution of Q55, R60, and E62 in the region comprising amino acids 51 to 63 of the mature wild-type neurturin and wherein the neurturin polypeptide has a decreased affinity to heparin compared to the mature wild-type neurturin.