GÉNÉRATION D'ANTICORPS CONTRE DES ANTIGÈNES TUMORAUX ET GÉNÉRATION DE CYTOTOXICITÉ DÉPENDANTE DU COMPLÉMENT SPÉCIFIQUE D'UNE TUMEUR PAR L'ADMINISTRATION DU VIRUS ONCOLYTIQUE DE LA VACCINE
The present invention relates to methods and compositions for use in inducing tumor-specific antibody mediated complement-dependent cytotoxic response in an animal having a tumor comprising administering to said animal a composition comprising a replication competent oncolytic virus wherein administration of the composition induces in the animal production of antibodies that mediate a CDC response specific to said tumor.