The invention is directed to compositions containing growth agents synthesizedfrom cultured cells from skin. Skin cells such as keratinocytes and dermalfibroblasts are cultured in vitro in cell medium and in the course of culturethe cultured cells synthesize and secrete agents into the cell medium. Themedium containing agents are collected and incorporated into pharmaceutical orcosmetic preparations to treat an individual. The preparation is applied andhas a rejuvenating effect on the cells and tissue.
