The present invention provides a use of small-molecule polysaccharides for the manufacture of an anhydrous composition of small-molecule polysaccharides for treating a patient with conditions caused by or relating to skin or exocrine glands, comprising (1) cleaning an area of skin of the patient and keeping the area dry, (2) applying the anhydrous composition of small-molecule polysaccharides to the area, the anhydrous composition of small-molecule polysaccharides consisting of at least a small-molecule polysaccharide and an anhydrous agent and the small-molecule polysaccharide having the size of about 12-22 nm, and (c) raising the temperature of the area with an external heating device. The use of the present invention increases the skin moisture, and thus achieves prevention or improvement of skin wrinkling and improvement of skin tightness and elasticity.本發明提供一種小分子多醣用於製造供治療患者之由皮膚或外分泌腺體所引起或與其相關之病狀之小分子多醣無水組成物之用途,包含:(1)清潔該患者皮膚的一區域並保持該區域乾燥,(2)將該小分子多醣無水組成物施加於該區域,該小分子多醣無水組成物由至少一小分子多醣及一無水基劑組成,且該小分子多醣的分子粒徑約12-22nm,以及(3)以一外部加熱裝置使該區域溫度上升。本發明之用途能提升皮膚含水量,進而達到預防或改善皮膚的皺紋形成、提高皮膚緊實度與彈性等功效。
