The present application relates to certain difluoropyrrolidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension.本申請案係關於特定二氟吡咯啶化合物、含其等之醫藥組合物及其等使用方法，包括治療物質成癮、恐慌症、焦慮、創傷後壓力症、疼痛、抑鬱、季節性情緒失調症、進食障礙或高血壓之方法。
