The present invention is related to a crude extract of mango flowers with antimicrobial function and a method of making the same. The discarded and fresh mango flowers and buds are subjected to a thermal reflow extraction process by a polar solvent without methanol, so as to extract the crude extract of mango flowers. The crude extract of mango flowers has a bioactivity against Staphylococcus aureus, thereby being applied on an external composition for skin.本發明是有關於一種具抗菌活性之芒果花粗萃物及其製造方法,其係將疏花被棄之愛文芒果的新鮮花苞與新鮮花,藉用不含甲醇之極性溶劑以加熱迴流萃取製程而獲得。由此所得的芒果花粗萃物具有抗金黃色葡萄球菌之活性,可應用於皮膚外用組成物。100‧‧‧方法101/103/105/107/109‧‧‧步驟