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Surface decontamination of preloaded containers in secondary packaging
专利权人:
NOVARTIS AG
发明人:
JÜRGEN SIGG
申请号:
BR112012000912
公开号:
BR112012000912A2
申请日:
2010.07.13
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
Methods and systems for the terminal sterilization and surface decontamination of prefilled containers containing sensitive drug products, such as biotech drug products that are otherwise temperature or radiation sensitive, and thus not suitable for terminal sterilization by classical methods involving steam or gamma rays. The methods and systems are especially suited for prefilled containers in secondary packaging. Methods include terminal sterilization by exposing prefilled containers in secondary packaging to tunable-beta radiation and further include terminal sterilization by exposing prefilled containers to controllable vaporized-hydrogen peroxide, including application of measures to reduce or prevent diffusion of vaporized-hydrogen peroxide into prefilled containers.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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