Disclosed herein is the use of an effective amount of a therapeutic agent which is 5-(fluoromethyl)piperdine-3,4-diol, 5-(chloromethyl)piperdine-3,4-diol, or a pharmaceutically acceptable salt, solvate, or prodrug thereof, or any combination of two or more thereof for the manufacture of a medicament for the treatment of a degenerative disorder of the central nervous system in a patient at risk for developing or diagnosed with the same.