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2-Aminoquinolines as 5-HT(5A) receptor antagonists
专利权人:
F. Hoffmann-La Roche AG
发明人:
Steward, Lucinda,Kolczewski, Sabine,Woltering, Thomas,Riemer, Claus,Wichmann, Juergen
申请号:
AU2007329064
公开号:
AU2007329064B2
申请日:
2007.11.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention relates to 2-Aminoquinoline derivatives which are representedby the general formula (I) wherein R, R and X are as definedin the specification as 5-HT receptor antagonists, their manufacture,pharmaceutical compositions containing them and their use as medicaments.Compounds of general formula I are useful in the prevention and/or treatmentof anxiety depression, anxiety disorders, schizophrenia, panic disorders,agoraphobia, social phobia, obsessive compulsive disorders, post-traumaticstress disorders, pain, memory disorders, dementia, disorders of eating behaviors,sexual dysfunction, sleep disorders, withdrawal from abuse of drugs, motordisorders such as Parkinson's disease, psychiatric disorders or gastrointestinaldisorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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