NIAZI, KAYVAN,RABIZADEH, SHAHROOZ,LE NY, ANNE-LAURE,BUZKO, OLEKSANDR,GOLOVATO, JUSTIN,SOON-SHIONG, PATRICK
申请号：
CA2939036
公开号：
CA2939036A1
申请日:
2013.12.11
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.
