COTE-DES-COMBES, SYLVAIN,FROISSANT, JACQUES,GIBERT, JEAN-FRANCOIS,MARGUET, FRANK,PACAUD, CHRISTOPHE,PUECH, FREDERIC,RAVET, ANTOINE
申请号：
CA2801154
公开号：
CA2801154C
申请日:
2011.06.01
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
Compounds corresponding to the general formula (I) in which R2 represents a group C1-10-alkyl, C3-10- cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkyl- C3-7-cycloalkyl, C3-7-cycloalkyl-C3-7-cycloalkyl, C1-6- alkylthio-C-1-10-alkyl, C1-6-alkoxy-C1-10-alkyl, hydroxy- C1-10-alkyl, hydroxy-C1-6-alkyl-C3-7-cycloalkyl-C1-6-alkyl, hydroxy-C3-10-cycloalkyl, C1-10-fluoroalkyl or C3-10- fluorocycloalkyl； an optionally substituted heterocyclic group； a group C1-10-alkyl substituted with an optionally substituted heterocyclic group； Xe represents a group chosen from hydrogen, fluorine, chlorine and bromine atoms or a group C1-6-alkyl, C3-7-cycloalkyl, C3-7- cycloalkyl-C1-6-alkyl, C1-6-fluoroalkyl or cyano； and R7 represents an aryl group such as phenyl or naphthyl, optionally substituted with one or more substituents, in the form of the base or of an acid-addition salt. Therapeutic use.
