UNIVERSITA DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO"
发明人:
GENAZZANI, ARMANDO A.,TRON, GIAN CESARE,GALLI, UBALDINA,TRAVELLI, CRISTINA,CUZZOCREA, SALVATORE,GROSA, GIORGIO,SORBA, GIOVANNI,CANONICO, PIER LUIGI
申请号:
CA2910255
公开号:
CA2910255A1
申请日:
2014.04.29
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Compounds of formula (I): able to inhibit nicotinamide phosphoribosyltransferase. The disclosure also relates to the use of compounds of formula (I) for treatment of pathological conditions in which NAMPT inhibition might be beneficial, such as acute and chronic inflammation, cancer and metabolic disorders.