process for producing 2- (3-cyano-4-isobutyloxyphenyl) -4-methyl-5-thiazolacarbocyclic acid form crystals

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专利权人:

TEIJIN PHARMA LIMITED

发明人:

AKIHITO UEMURA,TAKUMI TAKEYASU,TOMOAKI NOGATA

申请号：

BRPI1011671

公开号：

BRPI1011671A2

申请日:

2010.07.14

申请国别(地区):

BR

年份:

2016

代理人:

摘要：

Disclosed is a process for producing A-form crystals of 2-(3-cyamo-4-isobutytoxyphenyl)-4-methyl-5-thiazotecarboxylic acid, comprising: a step of dissolving by heating 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid in one or a plurality of solvents as a good solvent, selected from the group consisting of 1-propmol, 2-propanol, ethanol, and acetone, a step of cooling the solution； and a step of adding to the solution a hydrocarbon solvent as a poor solvent.

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