A system and method for positioning a medical imaging unit is disclosed. The method may include accessing data from a plurality of sensors. The method may also include computing an optimal position for the medical imaging unit to acquire images of a point of interest. The computation may be based on data from plurality of sensors and information for calibrating the point of interest with at least one sensor. The method may also include computing instructions for manipulating the medical imaging unit from a first position to an optimal position. In an embodiment, the instructions may be displayed for a user to manually position the medical imaging unit. Alternatively, the instructions may be sent to an electric motor to position the medical imaging unit, or the electric motor may provide force feedback to guide a user to position the medical imaging unit in an optimal position.