Systems and methods for digital radiography are provided. The method may be implemented on a DR system including an imaging device (110) and a computing device (200). The computing device (200) may include at least one processor (210) and at least one storage device (220). The method may include directing multiple dose sensors to detect a dose of radiation rays emitted from a radiation source of the imaging device (110). The multiple dose sensors may correspond to multiple imaging detectors, respectively. The method may also include determining the dose of the radiation rays. The method may further include directing, based on the dose of the radiation rays, at least one imaging detector of the multiple imaging detectors to proceed to detect the radiation rays for generating an image of a target object to be examined.
