PROBLEM TO BE SOLVED: To provide a therapeutic method for a human patient susceptible to glioblastoma or diagnosed with glioblastoma, in which an anti-VEGF antibody is used in combination with one or more additional antitumor therapeutic agents. A method for treating a patient diagnosed with glioblastoma, comprising an effective amount of anti-VEGF antibody, an effective amount of a chemotherapeutic agent, and an effective amount of radiotherapy, the method comprising: A method of treatment that prolongs the median overall survival of patients compared to glioblastoma patients who receive chemotherapy. Bevacizumab as anti-VEGF antibody and temozolomide as chemotherapeutic agent. [Selection diagram] None【課題】膠芽腫に罹患しやすい、又は膠芽腫と診断されたヒト患者に対し、抗VEGF抗体を、1種またはそれ以上のさらなる抗腫瘍治療剤と併用して行う治療方法の提供。【解決手段】有効量の抗VEGF抗体、有効量の化学療法薬、及び有効量の放射線治療を含む、膠芽腫と診断された患者の治療方法であって、抗VEGF抗体を用いずに該化学療法薬を投与される膠芽腫患者と比較して、患者の全生存期間中央値を延長させる、治療方法。抗VEGF抗体としてはベバシズマブ、化学療法薬としてはテモゾロミド。【選択図】なし