< Topic > The beshikuru constituent which is superior in time-dependant stability, offer the skin external use medicine and the cosmetics which include this.Solutions(1) the following component (A) and (B)(A) the ether non ionicity surface active agent which possesses the sterol skeleton(B) monoarukiruguriserirueteruThe beshikuru constituent which contains beshikuru which possesses the structure membrane which is included.(2) the following component (A) and (B)(A) the ether non ionicity surface active agent which possesses the sterol skeleton(B) monoarukiruguriserirueteruThe beshikuru constituent which contains beshikuru which possesses the structure membrane which is included is included, the skin external use medicine and the cosmetics.< Choice figure >It is not【課題】 経時安定性に優れたベシクル組成物、これを含む皮膚外用剤及び化粧料を提供すること。【解決手段】〔1〕 次の成分(A)及び(B);(A)ステロール骨格を有するエーテル系非イオン性界面活性剤(B)モノアルキルグリセリルエーテルを含む構成膜を有するベシクルを含有するベシクル組成物。〔2〕 次の成分(A)及び(B);(A)ステロール骨格を有するエーテル系非イオン性界面活性剤(B)モノアルキルグリセリルエーテルを含む構成膜を有するベシクルを含有するベシクル組成物を含む、皮膚外用剤及び化粧料。【選択図】なし