Patrick Couvreur,Didier Desmaele,Fatma Zouhiri,Reddy Harivardhan Lakkireddy
申请号：
US13126752
公开号：
US08748414B2
申请日:
2009.10.28
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to a complex made up of at least one molecule of statin or a derivative thereof, covalently bonded to at least one hydrocarbon radical including at least 18 carbon atoms and containing at least one 2-methyl-buta-2-ene unit, to nanoparticles of such a complex, and to a method for preparing same, said complex and/or said nanoparticles optionally being in the form of a lyophilizate. The present invention also relates to a pharmaceutical composition including at least one complex and/or nanoparticles such as previously defined. The invention finally relates to said complex and/or to said nanoparticles for the treatment and/or prevention of hyperlipemia and hypercholesterolemia.
