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LEVOTHYROXINE LIQUID FORMULATIONS
专利权人:
Hikma Pharmaceuticals USA Inc.
发明人:
Gurmukh Das Chanana,Ragheb M. AbuRmaileh
申请号:
US16776001
公开号:
US20200237695A1
申请日:
2020.01.29
申请国别(地区):
US
年份:
2020
代理人:
摘要:
A stable liquid formulation for parenteral administration that includes levothyroxine or a pharmaceutically acceptable salt thereof. The formulation includes a low concentration of an antioxidant, an amino acid as a pH adjuster and a stabilization agent in an aqueous solution that has a pH of about 9 to about 11.5. The parenteral liquid formulation is a stable formulation that is supplied as a ready-to-use or ready-to-administer product in a container or vial.
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