Systems for harvesting biological samples are provided that can include a first multi-well plate configured to support the growth of individual biological material within one or more of first wells of the first plate; and a second multi-well plate configured to couple with the first plate.Methods for harvesting biological samples are provided that can include providing first and second complimentary multi-well plates; growing individual biological material within the first plate; separating the individual biological material into first and second portions; and providing at least some of the second portion of the individual biological material into the second wells while maintaining at least some of the first portion within the first wells.Complimentary multi-well plates configured to couple in a stacked configuration are provided that can include a top plate having one or more open-bottomed wells and a bottom plate comprising one or more close-bottomed wells.