Systems and methods for removing plaque from blood vessels by applying constant or time varying magnetic or electrical fields. In one embodiment a system includes winding configurations positioned about a central axis along which a body region may be placed. Each winding configuration generates a magnetic field in a direction which passes through the body region. A first winding configuration generates a first magnetic field component perpendicular to a second magnetic field component generated by a second winding configuration. In a related method for removing a deposit of plaque from a position along a wall of a blood vessel a magnetic field is applied which has a net direction predominantly orthogonal to the direction of the flow of blood through the vessel.
