Eduardo Schiffrin;Dominique Brassart;Olivier Jacques Lantz;Kevin Burke Miller;Sebastian Diego Amigorena
发明人:
Eduardo Schiffrin,Kevin Burke Miller,Dominique Brassart,Olivier Jacques Lantz,Sebastian Diego Amigorena
申请号：
US13063589
公开号：
US09827216B2
申请日:
2009.09.11
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to methods and immunonutritional compositions for preventing or mitigating paralysis of the bone marrow, caused by a tumor or neoplasm, between cycles of and after anti-cancer therapy, thereby attaining a better efficacy of the treatment. More particularly, the present invention relates to methods and immunonutritional compositions that can transiently preventing or moderating, bone marrow paralysis or neutropenia of a subject tumor-induced apoptosis or necrosis or other cell damage such that the innate and adaptive immune functions and normal physiology of the bone marrow are preserved, at least in part, which, in turn, lead to (i) a better tolerance and increased efficacy to treatment； (ii) transient augmentation or enhancement of immunocompetence of the immune cell； and (iii) optimization of the effects of and increase of immunocompetence of the immune cell weakened due to paralysis of the bone marrow, caused by a tumor or neoplasm.
