It is a method of driving a MOS type imaging element in which pixels having sensitivities for different colors are arranged two-dimensionally, in which the imaging element has at least two types of read-out lines having different pixel arrangements to read out a charge signal of the pixels, and the method includes driving such that a read-out time interval of a charge signal of at least one type of read-out line among the read-out lines is longer than a read-out time interval of another type of read-out line and a charge accumulating period of each pixel of the one type of read-out line is longer than a charge accumulating period of each pixel of said another type of read-out line.