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ВОДОРАСТВОРИМАЯ ФАРМАЦЕВТИЧЕСКАЯ ПЛЕНКА С ПОВЫШЕННОЙ СТАБИЛЬНОСТЬЮ
专利权人:
ЗИМ ЛЭБОРАТОРИЗ ЛИМИТЕД
发明人:
Дауд, Анвар Сирадж,Сапкал, Нидхи Пракаш,Бонде, Минал Нандкумар
申请号:
EA201690751
公开号:
EA201690751A1
申请日:
2014.10.13
申请国别(地区):
EA
年份:
2016
代理人:
摘要:
the present invention includes oral thin film, which is \u0431\u044b\u0441\u0442\u0440\u043e\u0441\u043c\u0430\u0447\u0438\u0432\u0430\u0435\u043c\u043e\u0439, easily soluble, \u043d\u0435\u043f\u0440\u0438\u043b\u0438\u043f\u0430\u044e\u0449\u0435\u0439, \u043d\u0435\u043b\u0438\u043f\u043a\u043e\u0439 and \u043d\u0435\u0438\u0437\u0433\u0438\u0431\u0430\u044e\u0449\u0435\u0439\u0441\u044f, thus \u043a\u0430\u0437\u0430\u043d\u043d\u0430\u044f film can carry active ingredient for oral delivery, the film is \u0433\u0438\u0434\u0440\u043e\u043b\u0438\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0441\u0442\u0430\u0431\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0439 filmwhich retains its properties \u043d\u0435\u043f\u0440\u0438\u043b\u0438\u043f\u0430\u0435\u043c\u043e\u0441\u0442\u0438 and \u043d\u0435\u0438\u0437\u0433\u0438\u0431\u0430\u0435\u043c\u043e\u0441\u0442\u0438 under the impact of her 70\u00b15% relative humidity in the 25\u00b0\u0441, at least during the pe \u0440\u0438\u043e\u0434\u0430 time of 2 min to 2 h in the open state without packing, and process technology (way) of the film.the active ingredient may include without limitation of the active pharmaceutical ingredient, \u043d\u0443\u0442\u0440\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 or \u043a\u043e\u0441\u043c\u0435\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439.process \/ method, comprising (a) drying of cast film in two or more stages, (b) drying the film after molding are alternately on both sides (c) coating the \u0432\u044b\u0441\u0443\u0448\u0435\u043d\u043d\u0443\u044e film of synthetic \u0432\u043e\u0434\u043e\u043d\u0435\u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u044b\u0445 moisture resistant \/ water-resistant than some of the more hydrophobic polymers which do not melt at \u044b\u0441\u043e\u043a\u043e\u0439 temperature(d) the addition of synthetic \u0432\u043e\u0434\u043e\u043d\u0435\u0440\u0430\u0441\
来源网站:
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