A patch preparation having a backing layer and a drug layer laminated on the backing layer； wherein the drug layer contains an adhesive containing at least one compound selected from the group consisting of fentanyl and pharmaceutically acceptable salts thereof, polyisobutylene, and a silicon-containing polymer； and a mass ratio of the polyisobutylene and the silicon-containing polymer in the adhesive is 20:1 to 7:3.具備支持體、及該支持體上所層合之藥物層，藥物層係含有至少1種選自芬太尼(fentanyl)及該藥學上可容許的鹽所成群之化合物、及聚異丁烯、及含矽聚合物之黏著劑所成，黏著劑中之聚異丁烯及含矽聚合物之質量比為20：1~7：3之貼布劑。
