FRASER, CHRISTOPHER,KISHIMOTO, TAKASHI KEI,MALDONADO, ROBERTO A.
申请号:
CA2834532
公开号:
CA2834532A1
申请日:
2012.04.27
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class Il-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.