Christopher Fraser;Takashi Kei Kishimoto;Roberto A. Maldonado
发明人:
Christopher Fraser,Takashi Kei Kishimoto,Roberto A. Maldonado
申请号:
US13457999
公开号:
US20120276158A1
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes.