A MEDICINAL FUSIDIC ACID CREAM MADE USING SODIUM FUSIDATE AND INCORPORATING A BIOPOLYMER, MOMETASONE AS A CORTICOSTEROID AND CLOTRIMAZOL AS ANTIFUNGAL AGENT, AND A PROCESS TO MAKE IT
A Medicinal Fusidic Acid Cream Made Using Sodium Fusidate, A Corticosteroid, And An Antifungal Agent, And Incorporating A Biopolymer, And A Process To Make It The present invention is directed to a medicinal composition for treating skin inflammations, fungal/bacterial skin infections and related wounds, and also other skin wounds including those caused by burns. The cream also causes skin rejuvenation through an epithelisation process. The cream comprises a) a biopolymer in the form of Chitosan, b) active Pharmaceutical Ingredients (APIs), in the form of fusidic acid that has been generated in situ from sodium fusidate, Mometasone furoate & clotrimazole, c) a cream base containing primary and secondary emulsifiers, waxy materials, co-solvents, acids, preservatives, buffering agents, anti oxidants, chelating agents, and humectants, and d) water. The active ingredients, namely chitosan, Mometasone furoate, clotrimazole and fusidic acid, are incorporated in cream base for use in treating skin inflammations, fungal/ bacterial skin infections with allergy & itching, & wounds on human skin involving contacting human skin with the above identified composition. Fusidic acid of the cream is made in situ from Sodium Fusidate as the starting raw material, under oxygen-free environment.La présente invention concerne une composition médicinale pour traiter des inflammations cutanées, des infections cutanées fongiques/bactériennes et des plaies associées, ainsi que dautres plaies parmi lesquelles les plaies provoquées par les brûlures. La crème permet également la réjuvénation cutanée grâce à un processus dépithélisation. La crème comprend: a) un biopolymère sous la forme de chitosane, b) des principes actifs pharmaceutiques (API) sous la forme dacide fusidique généré in situ à partir de fusidate de sodium, de furoate de mométasone et de clotrimazole, c) une base de crème contenant des émulsifiants primaires et secondaires, des matériaux cireux, des co-solvants, des acides, des
